Precision Brain Access for Deep Brain Therapies

Millions of patients with Parkinson’s disease, Alzheimer’s disease, brain cancer, epilepsy, and other neurological disorders depend on therapies that must reach precise locations within the brain to be effective. NeuralGlider® is a validated precision brain access platform designed to improve target accuracy and support more effective delivery of brain-directed therapies. 

Actuated Medical Appoints Neurotechnology Leader JoJo Platt to Medical and Commercial Advisory Board. Accomplished neurotechnology strategist and ecosystem builder joins company to support commercialization, strategic partnerships, and investor engagement.

[Bellefonte, PA] - Actuated Medical, Inc., a clinical-stage medical device company focused on developing innovative technologies that improve patient care, today announced the appointment of JoJo Platt to its Medical and Commercial Advisory Board. Platt's appointment...

THE BOTTLENECK

The Bottleneck in Brain Therapeutics Is Not Only Biology — It Is Delivery

Breakthrough brain therapies are advancing rapidly, but their success depends on accurate delivery to precise brain targets. Even when the biological target is validated and the therapeutic payload is effective, clinical benefit can be limited if the therapy, implant, or device does not reach its intended location.

Actuated Medical is addressing this fundamental challenge with a developed and validated platform for precision brain access.

THE PLATFORM

Introducing the NeuralGlider® Precision Brain Access Platform

The NeuralGlider® platform uses electronically controlled ultrasonic motion to help maintain the desired trajectory during insertion through delicate brain tissue. In preclinical studies, it demonstrated precise delivery a AAV gene therapy to deep brain targets using a smaller-diameter cannula that showed healthier brain cells at the insertion site and less drug loss wicking back up the insertion track.

  • NHelps maintain the desired trajectory during insertion
  • NSupports precise access to deep brain targets
  • NPermits smaller-diameter cannulas for certain delivery applications
  • NReduces tissue trauma and therapeutic reflux
  • NEnables improved delivery across multiple brain-directed therapy categories