TEchnology

The NeuralGlider® Precision Brain Access Platform

A developed platform that uses electronically controlled ultrasonic motion to help maintain the desired trajectory during insertion through delicate brain tissue.

  • NDeep brain targets require precision
  • NElectronically controlled ultrasonic motion for access
  • NDesigned for access, placement, and delivery
  • NTrajectory control during insertion — compatible with AI-robotic positioning systems
  • NDeveloped and validated in multiple preclinical studies

The platform does not replace surgical planning, imaging, or navigation. It improves the physical insertion process by helping maintain the desired trajectory through brain tissue.

Evidence by the numbers
A network of research, publications, and validated results built over more than a decade.

Evidence

A Strong Scientific Foundation for Clinical Translation

More than a decade of development, federal funding, preclinical validation, global research adoption, peer-reviewed publications, and issued patents support the NeuralGlider platform.

Over 10-years of development and independent research supports translation to clinical use.

Learn more at ActuatedNeuroscience.com

Publications

Peer-reviewed publications citing NeuralGlider®

Global brain research laboratories using the technology

Scientific Publications and Research Foundation

The NeuralGlider® platform has been cited in 44+ peer-reviewed publications and used by leading global brain research laboratories worldwide.

Research Areas

  • NPrecision brain access and trajectory control
  • NAAV gene therapy delivery to deep brain targets
  • NReduced tissue trauma and therapeutic reflux
  • NSmaller-diameter cannula delivery methods
  • NDeep brain stimulation and neural interface access
Download a Summary of the publication List

Applications

Enabling Multiple Categories of Brain-Directed Therapies

One validated platform delivers accurate, repeatable access to deep brain targets — with clinical translation it will support therapies across the neuro landscape

Deep Brain Stimulation

Precise lead and electrode placement into deep nuclei to support consistent, well-targeted neuromodulation therapy.

Epilepsy Monitoring & Therapy

Accurate access for depth electrodes and localized therapy delivery in seizure-focus mapping and treatment.

CNS Gene Therapy

Targeted AAV and vector delivery to deep brain structures, demonstrated in preclinical studies.

Brain-Delivered Biologics

Controlled delivery of proteins and biologic payloads with smaller-diameter cannulas that may reduce reflux.

Neural Interfaces & BCI

Stable, low-trauma insertion of probes and interface arrays for next-generation brain–computer systems.

Regenerative & Restorative Therapies

Precise placement of cell-based and restorative therapeutics into targeted deep brain regions.